Browsing by Author "Christopher Gorman, Committee Chair"

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    Experimentation in Replacement Lithography, Reductive Desorption, and Scanning Probe Imaging on Various Metal Substrates.
    (2010-06-28) Williams, James Alfred; Christopher Gorman, Committee Chair; Edmond Bowden, Committee Member; Stefan Franzen, Committee Member; Lin He, Committee Member; Jack Odle, Committee Member
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    The Interaction of Boronic Acid Based Self-Assembled Monolayers as a Potential Glucose Sensor
    (2005-08-02) Allen, Angela M.; Christopher Gorman, Committee Chair; Charles B. Boss, Committee Member; Edmond F. Bowden, Committee Member; Kenneth W. Hanck, Committee Member
    Recognition of sugars such as glucose with phenylboronic acid–terminated self assembled monolayers (SAMs) was the basis for the designing and fabricating a biosensor. Self-assembled monolayers were formed on gold surfaces as shown by infrared spectroscopy. The continuous, repeatable increase of the electrochemical impedance as the concentration of glucose was increased gave indication of binding. This binding could be attributed to the precedent formation of relatively stable esters between phenylboronic acids and sugars. This impedance change upon binding between glucose and a phenylboronic acid-terminated SAM showed promise in the development of a glucose biosensor.
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    Issues in Patterning Self-Assembled Monolayers by Molecular Replacement: Comparison of Adventitious and Directed Replacement of One Molecule in a SAM with Another.
    (2010-12-20) Tucker, Eric; Christopher Gorman, Committee Chair; David Muddiman, Committee Member; Edmond Bowden, Committee Member; Gregory Parsons, Committee Member
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    Poly(lactic acid) Polymer Brushes as Dynamic Surfaces.
    (2011-01-05) Xu, Lebo; Christopher Gorman, Committee Chair; Jan Genzer, Committee Member; Edmond Bowden, Committee Member; Stefan Franzen, Committee Member; Lin He, Committee Member
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    Simple Molecule Mercury Sensor
    (2008-11-13) Wan, Yanjun; Edmond Bowden, Committee Member; Christopher Gorman, Committee Chair; David Shultz, Committee Member; Stefan Franzen, Committee Member
    Several molecules previously produced from a nitrile-based cascade cyclization were examined as potential mercury sensors. Various analytical parameters, including fluorescence quantum yield, UV shift, fluorescence quenching, binding constant, binding ratio, and lowest detection limit, were measured. The best mercury sensor molecule was found to be molecule 3c, which could be easily synthesized in gram quantities (3 steps, 55% overall yield). This molecule has a very high fluorescence quantum yield (Φ = 0.87), high sensitivity and selectivity towards mercury ion in both organic and aqueous media. The overall performance of molecule 3c is as good as, or better than, the majority of organic dye based mercury sensors reported to date.