Browsing by Author "King, Laura Stuart"

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    Development of Methodology to Synthesize (S)-Nicotine Derivatives
    (2004-02-12) King, Laura Stuart; Dr.Carl Bumgardner, Committee Member; Dr. Daniel L. Comins, Committee Chair; Dr.Jon Lindsey, Committee Member
    N-acylpyridinium salt chemistry was used to synthesize 4 substituted (S)-nicotine derivatives. The intermediate dihydronicotines and resulting nicotine derivatives serve as potential pharmaceutical and pesticide targets as well as interesting synthetic intermediates. Other methodologies developed synthesize (s)-nicotine-N-oxide.