Development of Methodology to Synthesize (S)-Nicotine Derivatives
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Date
2004-02-12
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Abstract
N-acylpyridinium salt chemistry was used to synthesize 4 substituted (S)-nicotine derivatives. The intermediate dihydronicotines and resulting nicotine derivatives serve as potential pharmaceutical and pesticide targets as well as interesting synthetic intermediates. Other methodologies developed synthesize (s)-nicotine-N-oxide.
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Keywords
nicotine-N-oxide, nicotine, n-acylpyridinium salt, dihydronictines
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Degree
MS
Discipline
Chemistry
