Characterization of Type I molecular markers in a line of pigs selected for increased litter size.

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dc.contributor.advisor Dr. Joseph Cassady, Committee Co-Chair en_US
dc.contributor.advisor Dr. Eugene Eisen, Committee Co-Chair en_US
dc.contributor.advisor Dr. O. W. Robison, Committee Member en_US Blowe, Charlotte Dawn en_US 2010-04-02T18:14:46Z 2010-04-02T18:14:46Z 2004-03-12 en_US
dc.identifier.other etd-03072004-123538 en_US
dc.description.abstract Direct selection for increased litter size was practiced for eleven generations in a Large White-Landrace composite line of pigs. Litters were standardized at birth so that no replacement gilts were reared in a litter with more than ten pigs. A contemporary control line was maintained. In generation nine, the estimated mean breeding value for litter size was 0.63 pigs greater in the select than control line. The objective of this research project was to test associations between Type I markers and response to selection. A candidate gene approach was employed to search for markers, which may explain some of the difference in litter size between the two lines. Two novel markers were discovered within the follistatin gene, which have shown associations with litter traits. The estrogen receptor marker was not segregating in the population of pigs used in this study. The retinol binding protein marker was segregating in the population studied; however the magnitude of allele frequency change was relatively small. Polymorphisms were not detected in other candidates tested. en_US
dc.rights I hereby certify that, if appropriate, I have obtained and attached hereto a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to NC State University or its agents the non-exclusive license to archive and make accessible, under the conditions specified below, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report. en_US
dc.subject reproduction en_US
dc.subject sus scrofa en_US
dc.title Characterization of Type I molecular markers in a line of pigs selected for increased litter size. en_US MS en_US thesis en_US Animal Science en_US

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