Development of an Internet Addressable Pneumatically Controlled Instrument for Applying Strain to Cells In-Vitro

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Title: Development of an Internet Addressable Pneumatically Controlled Instrument for Applying Strain to Cells In-Vitro
Author: Livingston, Frederick Jerard
Advisors: Edward Grant, Committee Chair
Ola Harrysson, Committee Member
John Muth, Committee Member
Abstract: Mechanical stimulation of tissue cells is a popular technique used by tissue engineering researchers to stimulate cell growth. This research requires an instrument that applies in-vitro compression and tension to individual cells, through mechanical loading. The mechanical load in the research reported on here is generated using a vacuum system under computer control. The vacuum system consists of a pneumatic valve that is proportionally controlled from a single board computer, and a pressure transducer to monitor the waveform of the applied mechanical loading. Because the computer control is based on a single-board computer, the mechanical loading of cells can be carried remotely using a network environment and a dedicated IP address. The system is a good example of a smart mechatronic system. The research and development was carried out with support from Flexcell International, a North Carolina based biotechnology company.
Date: 2006-06-14
Degree: MS
Discipline: Electrical Engineering
URI: http://www.lib.ncsu.edu/resolver/1840.16/538


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