False Selection Rate Methods in the Cox Proportional Hazards Model

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Title: False Selection Rate Methods in the Cox Proportional Hazards Model
Author: Chen, Yun
Advisors: Hao Zhang, Committee Member
Anastasios A. Tsiatis, Committee Member
Dennis D. Boos, Committee Co-Chair
Leonard A. Stefanski, Committee Co-Chair
Abstract: Variable selection methods are useful for distinguishing informative variables from uninformative variables. Many variable selection methods have been studied in linear regression models. Some methods have been extended to the Cox proportional hazards model based on the partial likelihood function. The False Selection Rate (FSR) variable selection method introduced by Wu, Boos and Stefanski (2006) is a new method applied to forward selection that controls the false selection rate of uninformative variables in the model by adding a number of phony variables to the original variables and calculating the proportions of the phony variables selected. In this work, we adapt the False Selection Rate procedure with the forward selection method (Forward-FSR) to the Cox proportional hazards model. In addition, we propose a new approach to estimate the tuning parameters in the penalty functions of the LASSO and the SCAD methods based on the False Selection Rate variable selection criterion. Under the Cox proportional hazards model, the three FSR methods, Forward-FSR, LASSO-FSR, and SCAD-FSR, are compared to forward selection with information criteria, to the LASSO and to the SCAD methods in simulation studies.
Date: 2006-07-27
Degree: PhD
Discipline: Statistics
URI: http://www.lib.ncsu.edu/resolver/1840.16/5530


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